When Should Potentially False Research Findings Be Considered Acceptable?

When Should Potentially False Research Findings Be Considered Acceptable?

Ioannidis estimated that most published research findings are false, but he did not indicate when, if at all, potentially false research results may be considered as acceptable to society. We combined our two previously published models to calculate the probability above which research findings may become acceptable. A new model indicates that the probability above which research results should...

Staphylococcus lugdunensis; a pathogen that should be considered in Iran

Background: Staphylococcus lugdunensis is Gram-positive cocci of the staphylococcaceae family. S. lugdunensis despite having a clotting factor (wall coagulase), was classified in the coagulase negative staphylococcus group (CoNS) for lack of free coagulase. Although this bacterium is part of the human normal flora, in terms of virulence, S. lugdunensis is in second place after S. aureus. S. lug...

Surgery for chronic aortic regurgitation: when should it be considered?

Deciding when to operate on a patient with chronic aortic regurgitation may be extremely difficult. The timing of surgery requires consideration of the etiology and pathophysiology of the aortic regurgitation, because aortic valve replacement carries morbidity and mortality that must be weighed against the potential problems of continued medical management. Guidelines for the use of surgery in ...

When should surgery be considered for the treatment of epilepsy?

When Should Two Minds Be Considered Versions of One Another?

What does it mean for one mind to be a different version of another one, or a natural continuation of another one? Or put differently: when can two minds sensibly be considered versions of one another? This question occurs in relation to mind uploading, where one wants to be able to assess whether an approximate upload constitutes a genuine continuation of the uploaded mind or not. It also occu...